Hi Dr. Huberman - My Dad has been a long sufferer of a movement disorder that is in part Small Vessell Disease (Atherosclerosis) of the Brain and Atypical Parkinsonism. I'm wondering if the Huberman Lab Nation would benefit from what one can do in their 30's, 40's, and 50's to help combat the genetic predisposition they've been dealt. In other words, what could I do, if anything, to alter a similar path to what my father is going thru in his late 70's? Are there proactive strategies, supplementation, exercise and or mental regimes one could participate in during these early decades? I believe the answer to this topic would be helpful for other neurodegenerative disorders of the brain and the listeners currently being affected by this. Thank You for all that you do Dr. Huberman; we are so grateful for your passion and purpose.
Exact behavior of dopamine Excluding hard & illegal drugs from the picture, why are dopamine peaks so bad if dopamine always goes up and then below baseline no matter what? Is dopamine over/below baseline always symmetrical -- i.e. equal and opposite and equivalent duration effects? If that's the case then pursuing things that stretch dopamine increase over hours/days might also be a bad idea, in some cases worse than some short-term drugs perhaps. So what is the exact behavior of dopamine in all such contexts?
Curiosity is both a state (a transient interest in something) and trait (curiosity drives interests that may last a lifetime). I'm interested to learn the science generally, and neuroscience in particular, if any is known, about what mechanisms lead to the state and trait of curiosity.
I’m sure this is a long shot, but if by any chance you it’d be a miracle. I have recently met a friend with brain lesions and she’s done all sorts of different modalities, by neurologists, according to her. I was hoping to find some updated research, maybe something one one missed, but I could hardly even find any at all. I’m not asking for a cure, but even a chance of a treatment working could be an option she ponders on. Recently heard you mention Dr. Nolan Williams.