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Supplements for G6PDd, the most common enzyme deficiency worldwide

Glucose-6-phosphate dehydrogenase deficiency affects 400 million people and predisposes them to red blood cell breakdown (a result of oxidative stress from poor glutathione recycling in the red blood cell). Most of the time, individuals affected have no symptoms. Some supplements mentioned in the scientific literature are vitamin B2, vitamin E, NAC, α-Lipoic acid, and liposomal glutathione. I believe a lot of people will benefit from Dr Huberman's thoughts.

bug in upgrading to lifetime?

I want to upgrade to lifetime but it wants to charge me $1,600 instead of $1,500 or $1,400… I think someone missed a +/- sign in the subscription management code.

ADHD

I’m 72 years old and can’t seem to organize my thoughts. Please don’t pay attention to age. I’m very fit and young. Brain scan was good. Frontal cortex to lit. What can I do?

Sleep

Often when I weak up, I weak up with headaches. It’s not every day happens. And I don’t have strong headaches, only that I feel I have a little pain, after weak up I take a cold shower and the pain it’s goes way. I have read try different sleep supplements I have try different methods but I could not solved till today. When you could give me some advice I will so grateful, thanks 🙏🏻. And I so grateful and thankful what you and all the Huberman team do for us thanks for everything, please keep doing I learn so much from you.

What are the cons of Caffeine and who should avoid it?

Hi Dr Huberman! I would like to ask what are the cons of caffeine usage? Who should avoid it? And what are the usage recommendations in terms of drinking (or even consuming in form of eg. capsules)? I recall the caffeine episode, but one thing that was missing for me was the one chapter about warnings and borders according to it. Origin of my question is that in my opinion many people tend to overuse it, and current culture of caffeine consumption tends to encourage and support it. Eg.: working overtime, social meetings, and growing market of energy drinks, and popular soda beverages including it. My doubts are associated with that, as far as i understand, that caffeine as a compound is in fact one of physically addictive substation (as a psychoactive stimulant). Some of my colleagues cant limit themselves to just one coffee per day and as far as i can see they are struggling with managing day/night cycle and as one form of trying to balance and improve sleep they really suffer or fail to put away coffee for some time. Besides that i'm not using caffeine at all due to being oversensitive to it and found myself way better sleeping and functioning without it at all, as well as i feel more peaceful, and managing to tackle stressful situations way better and with lot less anxiety than before. Thank you for the great job you have been doing! And all the best for this newly came year 2023. Tom