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Derealization and Depersonalization

Why do we develop these symptoms? Are they a symptom of an overall anxiety? Finally can it be turned off?

Strength vs hypertrophy, calisthenic vs gym

My understanding is that doing resistance training with higher weight and not many repetitions (3 to 5) increases mainly the strength but lowering the weights and doing more repetitions increases the muscle hypertrophy. If that’s correct, why is it that people practicing calisthenics are not that big, they don’t develop much hypertrophy but they are known to be very strong? In calisthenics you reach a point in which you cannot move heavier weights as you work with your body so you can only increase repetitions. I might be wrong and ask a silly question, by the way.

Hormones after Menopause

Hi, I am 56 and have been taking bio identical hormones for 3 yrs after being post meno for 4 yrs. I have regular cycles feel healthy, sleep well lost weight. I heard on David Sinclair podcast you mentioned that we are using up our vitality by doing this. Can you expand on this in anyway? I was so unwell before so I would choose to die sooner with a better quality of life than to age naturally with all the pain that comes with that. Thank you

Supplements

Thanks Dr. Huberman for your detailed analysis of "supplements" and how to approach making the selection for ourselves individually. I was wondering about your thoughts on Resveratrol, since you didn't mention it at all. In your podcast with Dr. Sinclair, Resveratrol was mentioned by him as one of his staple supplements to slow the aging process. Can you share some of your thoughts about that? Thanks in advance and thanks for all of your great work and podcast content!

Assessing sleep quality

What are the best means by which I can evaluate my sleep quality; that may be more objective. Are wearables such as a Garmin or Apple Watch accurate with the sleep data that they provide?