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Caffeine and the Gut Microbiome

Can caffeine have a detrimental effect on the gut microbiome? If so, under what conditions is this exacerbated (fasted, caffeine pill vs coffee, yerba mate etc)? Thanks for everything!

Is it ok to use Kratom daily?

I came across kratom a few years ago and have been using it regularly in place of stimulants like coffee. I've notice I also really like the mood lift, in addition to the energy lift. Its not the end of the world when I don't use it, but I prefer to use it. I read a few weeks ago about a lawsuit in the Bay Area (an addict said a drink with Kratom in it made him fall off the wagon after 7 years sobriety), and it made me wonder if there might be something unhealthy about using it. Can you clear this up? What are the potential negative effects of using it regularly? Is using it doing anything to my natural abilities to produce feel-good chemicals like dopamine? I'd love a balanced perspective on this, like your podcasts on alcohol, nicotine, etc.

Kratom

Effects and log term use effects of Kratom?

An episode dedicated to the neuroscience of creativity

In the cannabis episode, there was an interesting discussion about convergent and divergent thinking in regards to creativity. It would be great to have an episode dedicated to the neuroscience of creativity and some practical protocols.

Meditation

What are the benefits of meditation proven by neuroscience?