Can mouth taping really improve sleep and facial structure?
Dr. Huberman, what are your thoughts on the growing trend of mouth taping during sleep? Can nasal breathing at night actually reshape the face or improve sleep quality? And is there any neuroscience to support it? There is a trial by Cosimo Research attempting the biggest mouth taping trial ever - what are your thoughts on it? https://www.cosimoresearch.com/the-big-taping-truth-trial
MDMA effect on eyes, feature not a bug?
I have not been able to access any research on this specifically and I am not finding current studies through NIH RePORT. MDMA at fairly low doses is known to cause an effect on the visual system that results in what some users call "eye wobble." Given the know aberrations in eye saccades in a number of mental health conditions, and notably PTSD, I wondered if the effect of MDMA on eye movement might at all be a "feature" rather than a "bug?" Is it possible that part of the effect of MDMA on PTSD, aside from facilitating the openness to discuss or process trauma, might also be helped by the neurobiological processes that affect the eyes as well?
Treating cancer/autoimmune disease by interrupting DNA replication
For the past 9 years, I have been involved with a group of UCLA doctor/scientists currently in Phase 1 FDA trials for an orally administered enzyme, dCK, moderating DNA precursor uptake effectively controlling rapid cancer and immune cell growth with no appreciable impact on normal cell growth? Is this a cancer and autoimmune line of research you have heard of or explored? Trethera will present a poster at the Crohn’s & Colitis Congress (CCC) Annual Meeting. I'd like to get your informed opinion regarding such an approach.
Is there any valid data showing that scrolling on cell phones hinders physical performance due to mental fatigue?
I am a high school coach wrestling coach and weight training teacher. I came across a very vague study that suggested that scrolling on cell phones and looking at screens in general for extended periods of time causes a mental fatigue that could then cause a decrease in physical performance. Do you have any information to back this and if so, what can you provide that can then be communicated in a way to encourage students and staff from having students over using screens?
Space / Time Perception
How can we play around with the foveation of our eyes to expand or contract the way we perceive time? As you call it the fine slicing of time vs binning time in larger bins. How does that mechanism work? Besides the mechanics of the eye, I'm also specifically interested in the way we perceive color. Reds come forward in a painting and blues recede in space etc.. Thank you for educating us! Fabia
How to quickly find episodes I've already enjoyed
Andrew, I LOVE your podcast! (I can imagine you'd prefer the question content to be short but if you are interested in the "why" part of Love your podcast, I'll be glad to share). I believe the title asks the question but for a little additional detail, here it is: Sometimes, I'd like to be able to browse the episodes that I have already listened to. Is there a way to view a list of those episodes (I came to your website to look for the list as I am not able to find on Spotify and of course, I am not able to find it here either). Thank you! Robbie
Grateful for a Deep Dive: Freediving, Brainwaves & What Fish Might Know About Us
Dear Andrew, I'd like be the third person that gratefully requests an episode on freediving - and - this one could also include an other love of yours: fish. As you would know - there’s some incredible science emerging around what we can measure in elite freedivers—including (but not limited to) how they train themselves to influence autonomic functions once thought to be beyond conscious control, like heart rate, vascular tone, and even blood oxygen utilization. This feels like a natural fit for your protocol-based approach to health optimization, and they could give insight into the tools they use that you're audience could apply. But what really intrigues me about the practice is what’s still beyond the measurable. Maybe through an interview you can explore the states we can’t yet monitor at depth, like shifts in electromagnetic fields and nervous system coherence—and what that might mean for how we interact with marine life. As someone who's spent a lot of time in the water with fish, sharks included, I’ve come to believe there’s something very real in the idea that animals sense our intent. Many spearfishers, for instance, try to maintain a “neutral mind” to avoid alerting fish to their decision to take the shot - before they move a muscle to actually take the shot. The episode could be a part-science, part-spiritual —maybe in a similar style to your fantastic conversation with Martha Beck—featuring a freediver or other oceanic human who can speak to both the measurable and the mysterious. Something happens down there. Thats why we do science though right? To take us to the edge of the known and see into the mystery. Looking forward to your answer.
Podcast suggestion,
Beautiful day Dr. Andrew while listening to the podcast with Dr. HYMAN . In your discussion touch on American cuisine, and I would like to share a book I was reading from the library, of congress national library service titled Edna Lewis at the table with an American original By Sara B Franklin editor For me, the book is captivating the history of renown pioneer farm to table season cooking chef Edna Lewis Who introduced American cuisine southern cooking to the world, Edna Lewis worked developed a Southern cuisine using only fresh ingredients that is born out of Southern cooking. she worked in various. We're all right now restaurants in New York serving her inventive. This is Southern cooking to the cultural elite in New York. I would like to also share a YouTube video below regarding renown pioneer of American cuisine, Southern cooking, as well as writer, author of a taste of country cookbook so my suggestion for a podcast could you invite the editor Sarah be Franklin on your show to talk about fresh foods cooking and any type of scientific documents that support eating, organic fresh food is important brain health for children. https://youtu.be/zylIp4ZEtW0?si=TPApIpAdS7JDJbG7 YouTube video finding Edna Lewis episode three enjoy thank you
TRE
"Dr. Huberman, could you explore the TRE (Tension & Trauma Release Exercises) method in the context of trauma release, but also in relation to its broader effects on the nervous system? I use this method in my work as a psychotherapist and have observed benefits that seem to extend beyond trauma resolution—possibly impacting overall autonomic regulation and resilience. I'd be particularly interested to hear your take on the neurophysiological mechanisms behind these effects and whether you've encountered relevant research or personal insights into its potential for enhancing nervous system function more generally. Also, considering the growing interest in somatic and body-based therapies, it could be fascinating to hear a conversation between you and Dr. David Berceli, the founder of TRE, on the scientific foundations and future directions of this method."
Actinium-225 for my Father with Stage 4 Metastatic Prostate Cancer (Bone Metastasis)
I would like to know your expert opinion on Actinium- 225 and its prospects for patients who have exhausted all other treatment options. I’d specifically like to get your perspective on its efficacy, survival (OS and PFS) and its side effects. What other advanced technologies can you suggest for mitigation of pain and depression in patients like my father who are living their end game.
Back injury
I am a 24 year old male working in the trade industry in australia. 5 months ago i injured my back at work. I have been to several doctors and all say should of recovered by now but has not. I am doing exercises to strengthen my core which is helping slightly but it is still flaring up every time i pick something heavier than 10kg up even with good form. Scans are showing a slight herniated disc but not obstructing anything according to scans and l5/s1 disc is pretty trashed. Im looking into doing a few cycles of bpc-157 to see how it helps reduce inflammation and help with with the recovery. What if any indication are there of bpc-157 aiding in disc recovery or potential regeneration and helping with inflammation.
Can’t get more than 1 hr deep sleep.
How much deep sleep are you getting, Andrew? I’ve tried all the protocols, ALL of them and I hover around 12% of my total sleep of 8hrs. I’m a 38 yr old woman, physically fit and active, and I’ve only gotten the deep up around 16% total sleep 3 or so times in the past year.