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What does it mean to be untrained?

On the episode with Dr. Andy Galpin, Dr. Huberman mentioned that when he was young he followed a certain training regime that yielded good results due to him being "untrained" at the time. What does it mean to be untrained and why does it yield better results for physical training?

Keto + Fasting + muscle growth - body fat: is it possible and how?

Hi Dr. Huberman, like many others, I want to express my profound gratitude for your inspiring work. Your scientifically-backed health protocols have not only improved my health and lifestyle but also that of those I care for most! I've been grappling with a question that's difficult to get on the web : Is it feasible to gain muscle mass while on a keto and intermittent fasting regimen? Considering you are training for hypertrophy and low body fat(10-12%) If possible, could you suggest a protocol to maximize gains and reduce body fat simultaneously? How long does it take to re-enter ketosis after training fasted and then consuming a significant amount of carbs to refill glycogen stores? Is carb intake necessary for optimal gains? Is there another way to refill glycogen? What happens of I train and i dont eat for another 4-5h because i am fasting? Do iblose all the potential gains from that training? This also connects regarding the protein intake, if the recommendation is to consume it in the first 30 minutes for maximum absorption, and that fasting would have me starting to eat at noon and that i train at 6h, all of these combined is difficult to adjust with the best proptocols. how would you approach this? While these are many questions, they all revolve around the same subject. I hope this might inspire you to dedicate a podcast episode to this topic, delving into the details. I really hope you can decode all these questions and make some sense of it in whole, and if you dont you can always call me to get it directly from me! Haha Im sure youll have the time to do that! 514 812 3450 All jokes aside, thank you once again for all your guidance and support

Is it novelty, difficulty, or perdurance of challenge that triggers growth of the Anterior Mid-Cingulate Cortex?

I am persuaded & fascinated by your interpretation of the Colombe et al. "Aerobic Exercise Training Increases Brain Volume In Aging Humans" study, viz., that what triggered growth in the aMCC--with all its implied benefits for cognitive function and lifespan--was not so much the stimulus of aerobic exercise as the action of choosing to adopt a novel pattern of difficult action--and to stick to it. This raises a theoretical question with significant implications for how one would apply your interpretation practically in terms of a protocol, viz.: Which of the following are necessary and sufficient conditions of aMCC growth from challenge? A) Choosing to perform a hard action B) Choosing to perform a new action C) Sticking to/ repeating the performance of a new/hard action To put this question practically and concretely, if I were to use exercise as a protocol for attempting to trigger aMCC growth, which of the following would probably suffice? A) Repeatedly performing qualitatively similar but REALLY hard workouts--hard enough that they require activation of the will to overcome fear/ aversion to start? E.g.: not merely improving slightly & incrementally on running interval training by slightly increasing repetitions or speed, but adding enough repetitions or attempting to sustain so much speed that the probability of full success for any given workout is less than 90%, and pain is a certainty? B) Performing qualitatively new exercise--e.g., rock climbing, wrestling, something with a completely different physical pathway? C) If B) is required--much one stick with the new exercise and make into a new habit, as did the trainees in the study? Or is it actually better to cycle through a variety of new exercise regimens on a weekly basis? This emphasis on variety was once a feature of CrossFit training circa the early 2000s. This question may ultimately amount to a question about how aMCC growth is connected with task bracketing. If the aMCC is triggered by simply "doing hard things", i.e., sheer mental effort, then novelty of tasks will not be necessary so long as one keeps ratcheting up the difficulty of existing efforts. If novelty is required, but habit-forming is not required, then rotating a carousel of novel tasks that are entertaining--even though they are difficult--might be the answer. This does seem to be the spirit in which many highly functional elderly individuals approach their various hobbies. But if, finally, the optimal stimulus for aMCC development is connected to task bracketing, then that would suggest that the optimal protocol would involve sequentially choosing a qualitatively new, even scary task, mastering it by making it into a habit, and then moving on to another. I understand that the research may not exist yet to answer these questions definitively, but I would be grateful for any insight you could provide. Thanks, Ross

PTSD and or Bipolar with Lisa Feldman Barrett

I'd like to hear your dialog with Lisa as a follow up to your recent episode. Does the DSM-5 need to be scrapped? Are all mental health diagnoses constructs of millennia of misunderstanding of emotions? Are those with "PTSD" or "bipolar" simply misunderstood due to their "different" experience of emotional energetic states that don't fit into society's expectations?

Muscle weight vs fat

We often hear that muscle weighs more than fat, however when we’re overweight, lift weights, eat a calorie deficit, and still add weight on the scale, how possible is it that it’s muscle weight? How fast would it take to put on a pound of muscle vs. lose a pound of fat?