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Frequency of training to exhaustion.

Dear Prof Huberman, do you have any guidance on how often within a set or within a week one should you train to the point of failure? Or put another way what is the minimum dose and therapeutic window needed to achieve adaption muscular conditioning (vascularity and cellular conditioning). Reading the great book by Tim Ferris, "The Four Hour Body" implies doing too much can be counterproductive and can reduce other gains for example hypertrophy and increase the chance of injury. Currently I am doing one set to failure out of three in one muscle group. Thanks! James French

Brain Recovery

If one has formerly taken cocaine before and has now stopped, a study on rats you've shared shows that one can't learn because of the dendrites being damaged. Would the dendritic growth from Psilocybin offset this person's damage? Are there any other ways a person can recover quicker to have their most optimized brain?

CDB/Cannabis for sleep and anxiety

Is there any evidence to support CBD use for these issues? Can the isolated CBD have any effect beyond placebo? How is Cannabis affecting sleep?

Quick in-the-moment protocols for refreshing your brain

What are the most effective, in-the-moment protocols for refreshing your brain when it's fried from too much work and not enough sleep and you're in the middle of slamming out a big project with a looming deadline? Asking for a friend who may be in the middle of said project right now :) I try to get morning sunlight, enough sleep, good nutrition exercise etc, but what are the best things to do in say 5-10 minutes when you're in the midst of a very cognitively draining project and need to keep going? For example, short NSDR, cold shower, chocolate chip cookies, potato chips, jigsaw puzzles, nature walk, jumping jacks? Thank you, Dr Huberman!

The role of music in overall well-being and mental health in particular

Words are funny in that they mean everything, but can't say anything. I think this is why we have such a hard time describing emotions. We all think we know what ‘happy’ means, but when we try to explain it, it’s a struggle. Over time, humans have developed other ways to fill in the gaps through music. Music can powerfully impact our emotions and can be an effective tool for expressing ourselves and self-exploration. Ultimately, my question(s) is what does the science/research say about the role/impact of music as it relates to our mental health and whole-organism well-being? Is there a specific genre or style of music that is especially positively efficacious?