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New study shows gut bacteria triggers rheumatoid arthritis?

Autoimmune diseases are rampant in my family (Hashimotos, RA, alopecia). "The new study, published in the October 26 issue of Science Translational Medicine, revealed that this bacterial species could trigger the formation of autoantibodies, or antibodies that target the body's own tissues". Reference: ME Chriswell, et al. Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum. Science Translational Medicine DOI: 10.1126/scitranslmed.abn5166 (2022). If you could please do an episode on autoimmune diseases, I've been eagerly awaiting to hear an episode from you about this :D thankyou

Why doesn't Peter Attia do Zone 3 cardio?

In your Foundational Fitness Protocol, day 5 is 35 minutes of moderate intensity cardio (75-80% of max effort). My understanding is that this would fall into Zone 3 cardio. I've been listening to more of Peter Attia, and I noticed that he really only seems to do Zone 2 and Zone 5 cardio - in fact, he seems to emphasize how important these two zones are in particular because "that's generally where life takes place." So why do you include Zone 3 in your protocol? Does Attia emphasize 2 and 5 simply because he thinks that they are more practical for day-to-day life? Or are they actually more beneficial for overall health? Does Zone 3 have any distinct benefits to overall health?

Abstaining from Thoughts

Hello, in your discussion with Anna Lembke, you were talking about abstaining from people's drug of choice for 30 days to reset the dopamine reward pathway. You said you were going to ask Anna about how to abstain if your drug of choice was a thought and/or narrative. As far as I can tell, the discussion moved on before you could ask Anna that question. Would you be able to discuss strategies for abstaining from addictive thoughts and narratives?

Breastfeeding and vision

I'm a lactation consultant and am always in awe of the new things we learn about breast milk and the function of breastfeeding (oral development). There is evidence that breastfed babies have better vision, but mostly related to the composition of breast milk. My question is: Does the actual filling of the baby's mouth with mother's breast (The craniofacial anatomical factors and the biomechanics of the temporomandibular joints) and the angle baby is looking at the mother have any affect on the eye development or is it merely the composition of the milk? Thanks a lot Shaz

2C-B

I’ve listen to several podcasts about the effects of psychedelics and all the different ones, but I’ve just never heard you discuss 2C-B in depth I was just wondering if you have any insights into this drug?