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Enhancing stimulant medication effectivenes and reducing side effects

Hi Dr. Huberman, Thank you for the new podcast AMA format! I've recently been prescribed Vyvanse for treating ADHD. I find it's very effective in making me focus at work, but makes me suffer in most other aspects of my life. The main drawbacks I'm experiencing is the short duration (~6 hours compared to the advertised 12-14 hours), physical anxiety, high heart rate and blood pressure leading to not being able to exercise while on it. How do I help my psychiatrist solve these issues? Is there any suggestion I can make? Kind Regards, L

Ultradian Cycles, Chronotypes and sleeping patterns

In previous episodes, it was mentioned that most of us would be able to capitalize on an ultradian cycle around 9:30 am and 2 pm. We could also somewhat 'force' our body into a third one using caffeine and exercise as a tool. This all makes sense but my question is about the relevance of each chronotype. According to my genetic testing, I should wake around 8:50 am, I currently wake at 7 am and would like to attempt to fit three of these optimized ultradian cycles into my day. If I was to take at 7 am how would I achieve this? Also are Chronotypes relevant to our genetic sleeping patterns? Big thanks!

Nitrites & nitrates

Can you please explain difference between nitrites and nitrates in food? There seems to be quite a lot of confusion around these in general public.

Immune system/vaccine

Growing up I always accepted the idea of vaccines because they are just a normal part of modern-day health/life. But when I think about the history of humans it starts to not make so much sense to me. When the Spanish Conquistadors came to the Americas and killed tons of people, the virus didn't keep killing people throughout generations. The ones who survived made antibodies and when they had kids it's not like those kids needed a vaccine so that they wouldn't get sick from the same virus - they received the antibodies from their mom through breast milk and they were then inoculated to the virus. What I don't understand is if this is true. Then why is it a practice to vaccinate babies when they're born? Also, why is it normal for women to choose to formula feed vs breastfeed? I don't like speaking about this in public because I get labeled as a crazy anti-vaxer. But I just genuinely want to know the science behind it. IF I choose to not vaccinate my kids, are they at greater risk even if they're breastfed? Also, have there been any studies or data showing if there are risks associated with vaccinating babies? It would be cool if you could do a podcast with virologist or immunologist about this.

Difference between Endorphins and Dopamine?

Should we care about boosting Endorphins , and how ? Thanks .