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what toothpaste do you use?

My question is about whether fluoride toothpaste is safe to use. Are there any issues with stannous fluoride, sodium fluoride and sodium monofluorophosphate - to the central nervous system? Thank you

Have you talked aboout MCI

Any information on treatments for MCI? Here is a link to a study I participated in. https://evidence.nejm.org/doi/full/10.1056/EVIDoa2200121 I was in the crossword puzzle group.. I did well despite the crossword application being flawed. Time for each puzzle was 30 minutes. However,, if all squaares were not completed in 30 minutes a 0 was scored. As a result I set a timer for 28 minutes and started filling in blank squares with the letter D and if I happened to miss one,,a 0 was scored.. The application was on my PC and crossword clue sites were allowed. However, it was easy when hurriedly moving from the help tab to the crossword tab it was easy to accidently close it netting a 0 and only one puzzle a day was allowed. I don't know how much that may affected the score, but it sure was frustrating. and may mave lessened the crossword overall benefit.

Are shorter workdays optimal for knowledge workers in demanding disciplines

How much quality work do you think people who perform cognitively demanding work like mathematical research, theorem proving and so on for a living should expect them selves to be able to work per day? Some suggest short workdays like 2-4 hours and then taking the rest of the day off for resting and recovering their mental capacities for the next day's work. Others would suggest this seems lazy and that they can achieve more if they push themselves for longer hours.

Concentrating deep work to a four hour block vs. spreading it out throughout the day with big breaks inbetween

I have a desire to concentrate my deep work (mathematics), to 3-4 hours in the morning. This is because I find it difficult to do mathematics in the afternoons and evenings. I also take a long time to wind down after doing math and tend to burn out if I do it later in the day. However, you seem to think it is better to distribute the deep work throughout the day with breaks for two or more hours in between. Do you think it would be beneficial if I try harder to distribute my deep work throughout the day? And why exactly do you think we need two or more hours of rest in between deep work? Are there specific studies that demonstrate the importance of two+ hours of rest in between?

How can I tune down my excessively good moods?

Often when I feel good I feel more good than I want to. After exercising, having a pleasant social interaction and so on I often feel extremeley intelesely ecstatic, motivated and curious. These feelings are so intense it is hard to think clearly like I want to. They often last far too long. A workout at 2pm can leave me blissed out for many hours to such an extent it is hard to do work or other things I should do. A good conversation at 5pm can stimulate me so much it is hard to fall asleep at 10pm. How can I tune down my excessively good moods when I want to?