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Reducing sorenees from ultramarathon training

I'm about to start a training cycle for a 100K race in spring 2023. I'll be increasing my weekly mileage to ~60mi/week and running lots of trails to replicate the ~13,000ft of elevation gain on the course. I've been running consistently since early 2020 (at the start of COVID) and I'm always battling soreness. I've tried the Theragun, Normatec, 5-10min of nightly stretching, and ice baths after long runs, but I still find that I'm extremely sore. Do you have any tips on how to reduce soreness from lots of running? Thanks for your awesome podcast 🙏

Improve Sleep--deep and rem with diabetes

As an adult male with Type2 diabetes taking two types of insulin (Lantus-slow acting; Humalog-fast acting) have there been any studies done connecting low (or high) blood sugars (or even lowering A1c) to improving one's quality of sleep architecture including: 1) Deep Sleep and REM Sleep? 2) Because a non-diabetic's metabolizes energy (glucose) differently during the first part of the night vs the second part of the night--how is that different then a person with diabetes that injects insulin? 3) Using a DexCom6 CGM I occasionally experience hypoglycemic--does hypoglycemia affect the quality of Deep Sleep or REM Sleep more? Or both equally? 4) Would you consider doing a Huberman Lab podcast devoted to people with Type2 and Type1 diabetes?

Toolkit to help people lower baseline anxiety...

Would you ever consider creating a "toolkit" to help people reduce their baseline anxiety? This might help people who have experienced trauma and have high baseline anxiety. But it could also help people who experience certain times of life that raise their 'normal' baseline for extended periods of time. Your toolkits for sleep, exercise and focus are excellent! I just wondered if you could create one in this area. Thank you.

Hypoxic training - any benefits/dangers?

Please can I ask if there is any advantage/disadvantage to training with reduced oxygen? Some gyms are marketing this as a way to improve Vo2 max (30-minute sessions a few times a week). Thank you.

NAD+ related supplements to combat cellular aging

What is you take on supplements with Nicotinamide Riboside (NR-E)
 and/or Pterostilbene (PT)
 to boost NAD+? Useful for combatting cellular aging? For other purposes, such as maintaining circadian cycles?