Re: Dopamine - Morning physical training (Phase 1) after taking prescribed ADHD meds and possible dopamine crash in afternoon - ideal or not?
Hi Doc, I was curious if it may be better for me to do physical training (PT) during phase 2 rather than phase 1, given that I take ADHD meds. I generally avoid doing PT outside of my 0600-0800 window. I was prescribed ADHD meds almost a year ago and I have noticed mild crashes in the late afternoons on training days. I initially chalked this up to age but the more I thought about it, the more I realised this seemed to begin around the same time I started these meds. This has peaked my curiousity. After listening to your many podcasts and discussions on dopamine and epinephrine, and after reading the Molecule of More, it seems as if this may be a dopamine crash. I down regulate religiously after training sessions in order to cap my adrenaline, as Dr. Galpin suggested in one of your podcasts, and this has helped immensely, however, not entirely. Now, I know you recommend training during Phase 1, for various reasons. However, for someone like me, who is pharmacologically inducing dopamine as soon as I wake up (as per the dosing schedule), it seems to me that I may be better served training during Phase 2, so not to stack dopamine inducing actions and cause the release of too much. So my questions are these: 1) Does this make sense to you or am I wrong?; and 2) If I a wrong, when would be the best time to do resistance or CV for someone taking a stimulant in the mornings? or 3) Is this something I simply cannot avoid and it won't really matter? I am going to try trying during phase 2 for a few weeks and see what happens. I also plan to record the data so if you guys are lacking data in this area specifically, and are ever interested. Let me know and I can email it all to your lab. Thanks in advance!
TRE, Shivering & Fat Oxidation/Mobilization
There are already two questions about TRE (Trauma Release Exercise; developed by David Berceli? https://www.david-berceli.com) over here, but I'll add mine too. AFAIK, shivering during cold exposure is what facilitates fat oxidation/mobilization through local adrenaline release. Is it fair to say that the same mechanism would take place in case of the tremors/shivering that's the core of the Trauma Release Exercise? I'm currently doing TRE daily, right after my morning cold shower, and it warms me up quickly. I also don't feel hungry for several hours after TRE. So, perhaps, TRE is the sweet spot that helps to calm the mind (it does work for me), release the trauma over time, and help in fat loss as well. Since it's something everyone can do at home, at no cost (well, maybe after an intro workshop), it might be the sweet spot for many people :) Thank you for all that you do! Best wishes, Przemyslaw K. Radomski, CFA
Recovery from adolescent drug use.
Some background. I’m a 22 year old male who used alcohol and cannabis excessively in my first and second years of university (18 and 19 yrs old respectively). Thanks in large part to your recent podcast episodes on alcohol and cannabis, I’m now in a place where I may only use either substance once every 2-3 months or so. What recommendations would you give for recovering from any damage this heavy use may have had on my developing teenage brain?
Diagnosis - How To Diagnose and How to Effectively Challenge Diagnosis
Can you invite a guest to help walk us through the process of being properly diagnosed, the roadblocks we might face; and how to overcome them? Examples of proper diagnosis roadblocks: {}Accommodation versus Modification. My service dog was with me through all my tests, but the test results were equated as though that accommodation wasn’t made. No modifications were made. Diagnosis should be me - not me with another being. {}Doctor being unwilling to dx scarlet letter “dementia.” Even though it’s mathematically accurate since DSM no longer recognizes Persistent Post Concussion Syndrome, my proper dx since 3 months after an October 2006 car accident. {}Visual/construction neuro connection is 23:100 and language 19:100. Neuro - ophthalmologist and otolaryngologist testing showed physical function were on point. Told it must be a brain connection thing-but despite their titles, neuro-doctors said they can’t help. And thus, no other diagnosis accurately describes my medical condition, which is text book Persistent Post Concussive Syndrome. {}I’m willing to share my medical story.
Falling in love from the biological and chemical perspective
From the biological and chemical perspective, how can you fall ”in love” with someone – you accept her smell and body as a good biological match – but that person doesn’t reciprocate? It doesn’t ”feel” the same. Where does the chemistry ”go wrong” if that’s the case?