Ask Me Anything

with Huberman Lab Premium

Subscribe to ask a question

Adderall and Hypothalamus

Recently got my labs back and both my morning cortisol (5.8 ug/dL) and DHEA-S (142 ug/dL) were below the normal range. I'm a 36 year old male and generally healthy - stick to whole foods, supplement, strength train and do cardio. I do take Adderall though (5-7mg a day). I realize my results could be caused by a whole list of reasons on the highway between the hypothalamus and adrenal gland gland. But, was wondering if Adderall is somehow impacting the initial communication coming from the hypothalamus. Any insight you could provide would be appreciated. Thanks.

Recent AHA study on intermittent fasting

Good morning sir. First off, I love your podcasts. They are super informative. Im just looking to get your take on the latest news from the American Heart Assoc that intermittent fasting can lead to a 91% increase cardiovascular death. I’ve got my own feelings about the study which I don’t find all that comprehensive but would love to hear your thoughts. Thank you. Ken

European Tour?

hi im a long time fan and have found much guidance and help in your podcast and i would love to listen/see to you live! any chance of a European tour anytime soon?

Psychiatric comorbidities that co-exist with Adult ADHD - depression, anxiety, bipolar disorder, substance use disorder and personality disorders

Hello Dr Andrew Huberman - could you please talk about the common psychiatric comorbidities that co-exist with Adult ADHD including depression, anxiety, bipolar disorder, substance use disorder and personality disorders? I've been recently diagnosed with Adult ADHD by my Psychiatrist, shortly after, my Psychologist diagnosed me with severe depression and anxiety. I've been given a dexamfetamine as medication. My psychologist said if I feel better with the medication, the depression could be a chemical imbalance, if not I will need to undergo treatment like CBT. I would love to hear your insight and knowledge about the co-existing conditions with adhd. To be honest, the depression and anxiety diagnosis came as a surprise to me, I really thought I was doing well exercising, eating well and getting professional help, turns out I'm not. Thanks and looking forward for this to be covered in your podcast.

Antipsychotics & Low Motivation

Hi Andrew, I take Seroquel/quetiapine - an atypical antipsychotic - and it is working well in terms of what it is supposed to be doing for me. Still, it has sapped my motivation and ability to focus! My understanding is that the quetiapine blocks dopamine (is that correct?) - if that is the case, will doing dopamine-boosting activities (i.e., cold showers) help me regain my motivation to get up and do my work (I am a full-time student) and my ability to focus, or will the quetiapine also block the effects of that? Thank you!