Ask Me Anything

with Huberman Lab Premium

Subscribe to ask a question

Creatine’s effect on fat burning from increased glycogen

In the fat-burning episode, one of the topics covered was that the body uses glycogen stores before switching to burning fat, the timeframe for which depends on the intensity of the exercise. My understanding of Creatine is that it increases water storage in muscles, therefore allowing those muscles to store more glycogen. Assuming all of that is accurate, would taking Creatine regularly (5 grams per day) then be detrimental to fat loss? Or more specifically, would the increase in glycogen stores mean that one would have to exercise for longer periods relative to intensity to switch over to burning fat stores during that activity?

Gluten, leaky gut, blood brain barrier and leaky brain

Consumption of gluten triggers the release of zonulin which increases gut permeability leading to leaky gut. In the episode #86 you discussed the health risks of leaky gut caused by alcohol consumption. Given the cause of leaky gut by gluten/zonulin, isn't the consumption of gluten a much bigger issue for much bigger part of population than just celiaks? Also, is it true that gluten exorphins formed during gluten digestion can cross the blood brain barrier and cause the so-called leaky brain and other issues?

Seed oils - deeper dive and clarification

Thank you for the info about seed oils in the first AMA. Can you please follow up on the topic with these questions: - Are refined seed oils oxidised given their low stability? - Do oxidised seed oils present a health issue? - Are there actually any studies looking at the metabolic disease risks associated with seed oils consumption? If so, do they differentiate between cold pressed and refined seed oils? - Given your answer in the first AMA, is it correct that you dont see any health risks coming from the high omega–6 ratio of many seed oils? Thank you!

Question About The “Wall “Protocol Of Cold Exposure

I have a question about the episode of cold exposure. You mention if we count time during the cold exposure, finally, we will adapt to the cold, and will be hard to build mental toughness. So you recommend counting the “wall” in our mind during the cold exposure. However, I will imagine the same thing will still happen because the wall will decrease eventually as we repeat. I apologize maybe I misunderstand your meaning and my poor English level.

Stuttering

Hi Andrew, I hope you are doing well. I would like to share something that I struggle with every day, and that causes an immense amount of suffering in my life. My case of stuttering is slightly unusual, as I did not stutter as a child (and was exceptionally fluent and very talkative), but then started to stutter approximately after 12 and surprisingly I do not recall any specific thing that could cause it (brain injury or emotional trauma). My stutter is mild, and usually, I manage to hide it pretty well with different tips and tricks that I developed through the years (junk words/phrases, finding synonyms to problematic words etc.). Nonetheless, it bothers me sometimes when I can not say something that I want, which results in anxiety, low self-esteem etc. I have a couple of questions regarding this. I know there is no cure, but what are the most effective methods that are known to science at this point. What does the latest research says about stuttering, its causes, treatment, medication etc. Also, who are the most credible and knowledgible scientists/researchers that are working in this field (maybe I will look into their research or even contact them). Has Deep Brain Stimulation ever been used to treat stuttering? Thank you in advance. I would like to use this moment to thank you for your great work! The amount of time and effort you put into your educational content is tremendous. You have probably heard this many times, but you have helped so many people to improve their lives. You are an amazing human being! Keep it up and all the best!