The difference between glutamine and L-glutamine
The first time I heard about I-glutamine was from your podcast. I am thinking of purchasing it for a member of my family who has been fighting cancer. However, I am confused about the difference between glutamine and l-glutamine. I was wondering whether you could clear this confusion and share your opinion about it? Many thanks in advance.
Time restricted feeding and weight loss drugs
I've recently been started on a GLP1-GIP agonist medication (Mounjaro) for weight loss. It's effects in the GLP1-GIP pathway reduce appetite by inducing the feeling of fullness and by slowing gastric motility. I've also started time-restricted feeding and the protocol I use allows me to eat between 1pm and 7pm. My question is, would the benefits seen from extending the fasted state through time restricted feeding be counteracted by the effects of a prolonged feeling of satiety and slowed gastric motility from the medication?
First and second order effects of dopamine deprivation
In your recent interview with Dr. Peterson, you described the dopamine biological cascade and some classic rat experiments, where the rat was dopamine deprived and would not move one body length for food. Is this a first order effect of low dopamine (causing an inability to think into the future and predict the reward), or is this a second order effect due to the biological cascade and a potential deficit in epinephrine formed from dopamine, causing a general lack of "neural energy", thus leading to an inability to function in general? If both, is there any sense of which is the bigger driver?