Ask Me Anything

with Huberman Lab Premium

Ask a question

Sinclair supplement NMN no longer available on Amazon?

Hello all, I recently (Feb 2023) ordered (From Amazon) and have been using the Genex Formulas NMN 250 mg capsules. Today I went to try and reorder and Amazon has removed them from the site. The 250 mg and 500 mg variants are gone. When I searched the web, a site called revgenetics.com mentions that the decision by Amazon has been called an "Internal business decision" citing a 2013 court decision where Amazon admitted some dietary supplements are fake. The question to this group is whether it is worth continuing NMN via Dr. Sinclair's recommendation or whether the Amazon decision to remove the product probably has more behind the scenes and the NMN should be discontinued. Thanks for your thoughts and I do understand this is not a medical advice request. Best wishes, SMD

Vortioxetine and Prolactine + Testosterone levels

I'm 40. I just finished taking Vortioxetine (10mg) after 1 year of fighting depression. I'm good now but 3 weeks after finishing, I did the blood panel, testosterone, prolactin and more. Testosterone is at 350 now and prolactin is at the upper boundary. Should I give it more time, focus on lifting weights like I do right now, or is it something that requires some drug adjustements? I listened to the episode where you discussed prolactin and potential of B6 to fight it off, but after familiarizing myself with possibility to overdose B6, this does not look like a way to address it, does it?

Psilocybin and Colorblindness

There might be an episode I could get referred to about this, but I have a friend who has been red/green colorblind his entire life. Me and him ended up taking some magic mushrooms one time, and at some point during our trip he was wigging out because he got to the point during his trip where his rods and cones had finally aligned where he was able to see true color in simple things like grass. I found it fascinating for my friend to have this breakthrough, but of course was only temporary. Are there any current ongoing or past studies about psilocybin research and ways to treat colorblindness at all, or is the relationship between the two only during psychedelic trip?

Late afternoon/ evening reduction in willpower & motivation

Hi Dr Huberman, Apologies if this has already been asked & answered elsewhere, but is there a biological basis for a loss of willpower &/or motivation layer in the day? If so, do you have any tools to keep on keeping on? For example, I start out the day with the best of intentions in various aspects of life and whilst all is tracking well earlier on the day, when obstacles or stressors come on board, the willpower diminishes. A typical example is trying to eat healthily & then faced with work pressures, commuting, family pressures, will power evaporates all too quickly. Thanks I’m advance. Mark

Protein Powder Supplementation + Gut Dysbiosis

Can protein powder supplementation (either whey or plant-based) cause gut dysbiosis? I recently participated in a gut health test looking at the balance of good vs. bad bacteria in my microbiome, and my results skewed toward significantly more harmful bacteria present. As a vegetarian who prioritizes a large variety of plants and eats at least one serving of low-sugar, fermented food daily, I wonder if my protein powder intake (two servings per day) may be causing this harmful impact on my microbiome.